Yes, as mahanvey said, these are dangerous chemicals. The use of protective gloves and other safety equipment is highly!! recommended!!! I'm never around the stuff unless I'm in a full Tyvek chem-suit and gloves with a minimum of at least a respirator and the all important goggles. When we spray a hoody with an outside air source added with these layers of protection, and our spray booths will cycle the entire air in the room in less than 5 seconds. I don't even bother mixing my own adhesives at home because it's cheaper, easier and safer to just buy the stuff. If you do I hope you do it safely!